Improved Walking Capabilities after Eight Weeks of Hal® Exoskeleton-Supported Treadmill Therapy in a Patient with Limb-Girdle Muscular Dystrophy Type 2I

نویسندگان

  • Matthias Sczesny-Kaiser
  • Rebecca Kowalewski
  • Mirko Aach
  • Dennis Grasmücke
  • Matthias Vorgerd
  • Martin Tegenthoff
چکیده

Objective: HAL® robot suit is a new voluntary driven exoskeleton for the lower limbs. It has already been demonstrated to improve walking functions in spinal cord injury and stroke patients. So far, it is not known if HAL® training may be beneficial in patients with limb girdle muscular dystrophy, too. Design/methods: In this short report, HAL® exoskeleton assisted body-weight supported treadmill training has been applied in a patient with limb-girdle muscular dystrophy type 2I for eight weeks (3 times × 8 weeks = 24 sessions). For training success, standardized walking tests were assessed prior and after training session, and after 6 weeks serving as follow-up measurement (10-meter-walk test, 6-minute-walk test, timed-up-and-go test). Results: The patient improved in all walking functions. Follow-up measurements showed outlasting effects after 6 weeks without HAL® training. No adverse events occurred. Conclusions: HAL®-supported treadmill training canto be a promising new rehabilitation approach also for patients with muscular dystrophy. Systematic clinical trials with respect to genetic LGMD subtype should prove beneficial effects in a larger cohort.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Treadmill Training with HAL Exoskeleton—A Novel Approach for Symptomatic Therapy in Patients with Limb-Girdle Muscular Dystrophy—Preliminary Study

Purpose: Exoskeletons have been developed for rehabilitation of patients with walking impairment due to neurological disorders. Recent studies have shown that the voluntary-driven exoskeleton HAL® (hybrid assistive limb) can improve walking functions in spinal cord injury and stroke. The aim of this study was to assess safety and effects on walking function of HAL® supported treadmill therapy i...

متن کامل

Association of Limb-Girdle muscular dystrophy with multiple sclerosis: A case report

Background: The association of limb-girdle muscular dystrophy (LGMD) with other neurological disorders is uncommon. Case presentation: We report a 25-year-old female with LGMD who suffered from slowly progressive proximal muscular weakness and atrophy since she was 12 years of age. The patient recently presented with acute loss of left side visual acuity. After evaluation, findings were sugges...

متن کامل

Clinical and molecular characterization of patients with limb-girdle muscular dystrophy type 2I.

BACKGROUND Limb-girdle muscular dystrophy type 2I is caused by mutations in the fukutin-related protein gene (FKRP). FKRP encodes a putative glycosyltransferase protein that is involved in alpha-dystroglycan glycosylation. OBJECTIVES To identify patients with limb-girdle muscular dystrophy type 2I and to derive genotype-phenotype correlations. DESIGN Two hundred fourteen patients who showed...

متن کامل

Risk factors for osteoporosis, falls and fractures in hereditary myopathies and sporadic inclusion body myositis — A cross sectional survey☆

BACKGROUND The risk of osteoporosis is known in myopathies requiring long-term steroid treatment and Pompe disease, but not in other hereditary myopathies or sporadic inclusion body myositis (sIBM). METHODS Risk factors of osteoporosis, laboratory parameters of bone metabolism, frequency of falls and fractures, walking ability, and pain were surveyed using questionnaires in 89 patients with s...

متن کامل

Genetic basis of limb-girdle muscular dystrophies: the 2014 update

Limb-girdle muscular dystrophies (LGMD) are a highly heterogeneous group of muscle disorders, which first affect the voluntary muscles of the hip and shoulder areas. The definition is highly descriptive and less ambiguous by exclusion: non-Xlinked, non-FSH, non-myotonic, non-distal, nonsyndromic, and non-congenital. At present, the genetic classification is becoming too complex, since the acron...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016